Liposomal Delivery Technology for Superior Nutrient Absorption

June 15, 2021

Liposomal Delivery Technology for Superior Nutrient Absorption

What are liposomes?

Liposomes are spheres made of phospholipids—the primary building blocks of cell membranes. Owing to this structure, liposomes bond easily with cell membranes to facilitate intracellular delivery of their nutrient cargo. Thanks to this enhanced delivery and absorption, nutrients delivered in the liposomal form at lower doses may have equal or greater efficacy than higher doses provided in forms that are less bioavailable.

Liposomal particles: increased oral & cellular uptake, faster transmucosal absorption

Designs for Health’s liposomal products employ liposome particles that are 50-100nm in size, in contrast to 200-600nm particles that are more commonly available from other manufacturers. The smaller sized particles result in increased oral and cellular uptake and faster transmucosal absorption in the mouth, in addition to enhanced absorption throughout the rest of the gastrointestinal tract. In fact, it is recommended to hold the product in the mouth for several seconds before swallowing to take advantage of this effective route of absorption. Additionally, clearance of these particles from the bloodstream (via the liver and spleen) is inversely related to size: the smallest particles circulate the longest. Note that the phospholipids used in DFH’s new liposomal products are derived from sunflower lecithin (non-soy, non-GMO material).

Why liposomal formulations?

  • Superior absorption and intracellular delivery of nutrients
  • Phospholipid structure allows for effective delivery of compounds with different solubilities carried within the same particle (e.g., water- and fat-soluble compounds)
  • Liposomes penetrate the blood-brain barrier, an obstacle for other various formulations
  • While there is an opportunity for quick absorption in the mouth, liposomes also survive the acidic environment of the stomach, ensuring intestinal uptake and delivery to the lymphatic system
  • Liquid liposomal formulations are convenient for those who prefer to swallow fewer pills; also allow for easy dosing
  • Increased bioavailability may mean a lower dose is needed, potentially translating into reduced costs for patients

Advantages of Liposomal Delivery

Unilamellar Liposome

 

Liposomal Technology


Research by Designs for Health USA Michael Jurgelewicz, DC, DACBN, DCBCN, CNS

ORIGINAL ARTICLE; Designs for Health

https://www.designsforhealth.com.au/liposomal-technology-new-delivery-form-for-superior-absorption/

SHOP DFH products HERE




Leave a comment

Comments will be approved before showing up.


Also in holistic health science

The Latest on Glutathione
The Latest on Glutathione

July 14, 2022

Glutathione is a critical participant in the body’s response to oxidative stress. It continues to be of interest to the research community as emerging evidence broadens our understanding of this vital molecule. 

Continue Reading

The Latest on the Microbiome-Gut-Brain Connection
The Latest on the Microbiome-Gut-Brain Connection

June 27, 2022

Studies with germ-free (GF) animals show many changes in brain health, including a decrease in tight junctions between cells, an increase in the permeability of the blood-brain barrier (BBB) and a reduction in brain-derived neurotrophic factor (BDNF). BDNF is a protein that plays an essential role in synaptic plasticity, nervous system modulation, memory formation, and neurons’ growth, maintenance, and survival. Studies have also demonstrated that GF animals experience increases in anxiety-like behaviour, a decrease in sociability, and decreases in brain size. 

Continue Reading

Botanical Therapy for Antibiotic Resistance in the GI Tract
Botanical Therapy for Antibiotic Resistance in the GI Tract

April 07, 2022

Antibiotic resistance occurs when microorganisms develop the ability to overcome the antibiotics designed to kill them. Bacteria have numerous strategies to resist antibiotics. 

Testing for AR genes can help to characterise resistant infections and can aid in selecting effective therapies. Some of the key AR strategies are detailed below.

Continue Reading