nav

Liposomal Delivery Technology for Superior Nutrient Absorption

June 15, 2021

Liposomal Delivery Technology for Superior Nutrient Absorption

What are liposomes?

Liposomes are spheres made of phospholipids—the primary building blocks of cell membranes. Owing to this structure, liposomes bond easily with cell membranes to facilitate intracellular delivery of their nutrient cargo. Thanks to this enhanced delivery and absorption, nutrients delivered in the liposomal form at lower doses may have equal or greater efficacy than higher doses provided in forms that are less bioavailable.

Liposomal particles: increased oral & cellular uptake, faster transmucosal absorption

Designs for Health’s liposomal products employ liposome particles that are 50-100nm in size, in contrast to 200-600nm particles that are more commonly available from other manufacturers. The smaller sized particles result in increased oral and cellular uptake and faster transmucosal absorption in the mouth, in addition to enhanced absorption throughout the rest of the gastrointestinal tract. In fact, it is recommended to hold the product in the mouth for several seconds before swallowing to take advantage of this effective route of absorption. Additionally, clearance of these particles from the bloodstream (via the liver and spleen) is inversely related to size: the smallest particles circulate the longest. Note that the phospholipids used in DFH’s new liposomal products are derived from sunflower lecithin (non-soy, non-GMO material).

Why liposomal formulations?

  • Superior absorption and intracellular delivery of nutrients
  • Phospholipid structure allows for effective delivery of compounds with different solubilities carried within the same particle (e.g., water- and fat-soluble compounds)
  • Liposomes penetrate the blood-brain barrier, an obstacle for other various formulations
  • While there is an opportunity for quick absorption in the mouth, liposomes also survive the acidic environment of the stomach, ensuring intestinal uptake and delivery to the lymphatic system
  • Liquid liposomal formulations are convenient for those who prefer to swallow fewer pills; also allow for easy dosing
  • Increased bioavailability may mean a lower dose is needed, potentially translating into reduced costs for patients

Advantages of Liposomal Delivery

Unilamellar Liposome

 

Liposomal Technology


Research by Designs for Health USA Michael Jurgelewicz, DC, DACBN, DCBCN, CNS

ORIGINAL ARTICLE; Designs for Health

https://www.designsforhealth.com.au/liposomal-technology-new-delivery-form-for-superior-absorption/

SHOP DFH products HERE




Leave a comment

Comments will be approved before showing up.


Also in holistic health science

Botanical Therapy for Antibiotic Resistance in the GI Tract
Botanical Therapy for Antibiotic Resistance in the GI Tract

April 07, 2022

Antibiotic resistance occurs when microorganisms develop the ability to overcome the antibiotics designed to kill them. Bacteria have numerous strategies to resist antibiotics. 

Testing for AR genes can help to characterise resistant infections and can aid in selecting effective therapies. Some of the key AR strategies are detailed below.

Continue Reading

Recent Review Explores Health-Supportive Properties of Ganoderma Lucidum Extracts
Recent Review Explores Health-Supportive Properties of Ganoderma Lucidum Extracts

October 26, 2021

Ganoderma lucidum is commonly known as the reishi mushroom with a well-established role in East Asian medicine that has been used for centuries. G. lucidum polysaccharides (GLPs) are constituents of the whole plant that have been shown to support the body’s response to oxidative stress, immune function, and many other pathways and functions.

Continue Reading

Phytosterol May Influence Cholesterol Absorption and Healthy Lipid Metabolism
Phytosterol May Influence Cholesterol Absorption and Healthy Lipid Metabolism

October 26, 2021

Phytosterols are compounds present in most plant cells that contribute to the structure and stability of membranes. Phytosterols are fat-soluble compounds that are similar in structure to cholesterol (the most abundant sterol of animal cells). Hundreds of phytosterols have been identified from plant cells, including beta-sitosterol, brassicasterol, campesterol, and avenasterol. Phytosterols are present in legumes, seeds, and oily fruits, such as pistachios.

Continue Reading